Plant Transcription Factor Database
Previous version: v3.0
Brassica napus
ZF-HD Family
Species TF ID Description
GSBRNA2T00000979001ZF-HD family protein
GSBRNA2T00004355001ZF-HD family protein
GSBRNA2T00006560001ZF-HD family protein
GSBRNA2T00009837001ZF-HD family protein
GSBRNA2T00009839001ZF-HD family protein
GSBRNA2T00010909001ZF-HD family protein
GSBRNA2T00011403001ZF-HD family protein
GSBRNA2T00014591001ZF-HD family protein
GSBRNA2T00016187001ZF-HD family protein
GSBRNA2T00017701001ZF-HD family protein
GSBRNA2T00027325001ZF-HD family protein
GSBRNA2T00030829001ZF-HD family protein
GSBRNA2T00035627001ZF-HD family protein
GSBRNA2T00036365001ZF-HD family protein
GSBRNA2T00040522001ZF-HD family protein
GSBRNA2T00041709001ZF-HD family protein
GSBRNA2T00055163001ZF-HD family protein
GSBRNA2T00055796001ZF-HD family protein
GSBRNA2T00056334001ZF-HD family protein
GSBRNA2T00060813001ZF-HD family protein
GSBRNA2T00063746001ZF-HD family protein
GSBRNA2T00064772001ZF-HD family protein
GSBRNA2T00067727001ZF-HD family protein
GSBRNA2T00073390001ZF-HD family protein
GSBRNA2T00079301001ZF-HD family protein
GSBRNA2T00079503001ZF-HD family protein
GSBRNA2T00081698001ZF-HD family protein
GSBRNA2T00081930001ZF-HD family protein
GSBRNA2T00083685001ZF-HD family protein
GSBRNA2T00089537001ZF-HD family protein
GSBRNA2T00095755001ZF-HD family protein
GSBRNA2T00096525001ZF-HD family protein
GSBRNA2T00099388001ZF-HD family protein
GSBRNA2T00099428001ZF-HD family protein
GSBRNA2T00101922001ZF-HD family protein
GSBRNA2T00102750001ZF-HD family protein
GSBRNA2T00102909001ZF-HD family protein
GSBRNA2T00103573001ZF-HD family protein
GSBRNA2T00103631001ZF-HD family protein
GSBRNA2T00109394001ZF-HD family protein
GSBRNA2T00109603001ZF-HD family protein
GSBRNA2T00109606001ZF-HD family protein
GSBRNA2T00112888001ZF-HD family protein
GSBRNA2T00114284001ZF-HD family protein
GSBRNA2T00116082001ZF-HD family protein
GSBRNA2T00129223001ZF-HD family protein
GSBRNA2T00134800001ZF-HD family protein
GSBRNA2T00135543001ZF-HD family protein
GSBRNA2T00136551001ZF-HD family protein
GSBRNA2T00136580001ZF-HD family protein
GSBRNA2T00136855001ZF-HD family protein
GSBRNA2T00139558001ZF-HD family protein
GSBRNA2T00142504001ZF-HD family protein
GSBRNA2T00142864001ZF-HD family protein
GSBRNA2T00142868001ZF-HD family protein
GSBRNA2T00143637001ZF-HD family protein
GSBRNA2T00143692001ZF-HD family protein
GSBRNA2T00144536001ZF-HD family protein
GSBRNA2T00144539001ZF-HD family protein
GSBRNA2T00148816001ZF-HD family protein
GSBRNA2T00149051001ZF-HD family protein
GSBRNA2T00151336001ZF-HD family protein
ZF-HD Family Introduction

This group of sequences described by a 54-residue domain found in the N-terminal region of plant proteins, the vast majority of which contain a ZF-HD class homeobox domain toward the C terminus. The region between the two domains typically is rich in low complexity sequence. The companion ZF-HD homeobox domain is described in INTERPRO:IPR006455.

A one-hybrid screen resulted in the cloning of four different members of a novel class of plant homeodomain proteins, which are most likely involved in the mesophyll-specific expression of the C4 PEPCase gene in C4 species of the genus Flaveria. Inspection of the homeodomains of the four proteins reveals that they share many common features with homeodomains described so far, but there are also significant differences. Interestingly, this class of homeodomain proteins occurs also in Arabidopsis thaliana and other C3 plants. One-hybrid experiments as well as in vitro DNA binding studies confirmed that these novel homeodomain proteins specifically interact with the proximal region of the C4 PEPCase (C4 phosphoenolpyruvate carboxylase) gene. The N-terminal domains of the homeodomain proteins contain highly conserved sequence motifs. Two-hybrid experiments show that these motifs are sufficient to confer homo- or heterodimer formation between the proteins. Mutagenesis of conserved cysteine residues within the dimerization domain indicates that these residues are essential for dimer formation. Therefore, we designate this novel class of homeobox proteins ZF-HD, for zinc finger homeodomain protein. Our data suggest that the ZF-HD class of homeodomain proteins may be involved in the establishment of the characteristic expression pattern of the C4 PEPCase gene.

Windhovel A, Hein I, Dabrowa R, Stockhaus J.
Characterization of a novel class of plant homeodomain proteins that bind to the C4 phosphoenolpyruvate carboxylase gene of Flaveria trinervia.
Plant Mol Biol. 2001 Jan;45(2):201-14.
PMID: 11289511